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Abstract

Bioinformatics is a fast-growing field based on the optimal use of "big data" gathered in genomic, proteomics, and functional genomics research. In this paper, we conduct a comprehensive and in-depth bibliometric analysis of the field of bioinformatics by extracting citation data from PubMed Central full-text. Citation data for the period 2000 to 2011, comprising 20,869 papers with 546,245 citations, was used to evaluate the productivity and influence of this emerging field. Four measures were used to identify productivity; most productive authors, most productive countries, most productive organizations, and most popular subject terms. Research impact was analyzed based on the measures of most cited papers, most cited authors, emerging stars, and leading organizations. Results show the overall trends between the periods 2000 to 2003 and 2004 to 2007 were dissimilar, while trends between the periods 2004 to 2007 and 2008 to 2011 were similar. In addition, the field of bioinformatics has undergone a significant shift, co-evolving with other biomedical disciplines.

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Abstract

To understand the current state of a discipline and to discover new knowledge of a certain theme, one builds bibliometric content networks based on the present knowledge entities. However, such networks can vary according to the collection of data sets relevant to the theme by querying knowledge entities. In this study we classify three different bibliometric content networks. The primary bibliometric network is based on knowledge entities relevant to a keyword of the theme, the secondary network is based on entities associated with the lower concepts of the keyword, and the tertiary network is based on entities influenced by the theme. To explore the content and properties of these networks, we propose a tomographic content analysis that takes a slice-and-dice approach to analyzing the networks. Our findings indicate that the primary network is best suited to understanding the current knowledge on a certain topic, whereas the secondary network is good at discovering new knowledge across fields associated with the topic, and the tertiary network is appropriate for outlining the current knowledge of the topic and relevant studies.