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Abstract

Koma - Immer wieder stehen Ärzte vor der schwierigen Frage, ob ein Patient, der völlig teilnahmslos daliegt, nicht doch noch Gedanken und Gefühle hegt. Ein neues Verfahren erlaubt es, den Grad des Bewusstseins erstaunlich zuverlässig zu messen.

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Abstract

Bewusstsein ist und bleibt ein neurobiologisches Rätsel. Oder doch nicht? In diesem Interview, das Arvid Leyh im Jahr 2010 führte, berichtet Christof Koch, Professor für Kognitive Biologie und Verhaltensbiologie am California Institute of Technology (neu erschienen im April 2012: Christof Koch: Consciousness. Confessions of a Romantic Reductionist, http://www.science-shop.de/artikel/11...), inspirierend über seine Erkenntnisse bei der Suche nach neuronalen Korrelaten des Bewusstseins, die er in jahrelanger Forschung gemeinsam mit dem inzwischen verstorbenen Entdecker der Molekularstruktur der Erbsubstanz DNA, Francis Crick, gewann. NCCs, die neuronalen Korrelate des Bewusstseins sind definiert als der kleinste Satz neuronaler Ereignisse, der für eine bestimmte bewusste Wahrnehmung hinreichend ist.

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Abstract

Wie kann Aktivität im Gehirn Gefühle auslösen? Wie kann "bloßes Fleisch" - so wird der Körper in Cyberpunkromanen oft abfällig genannt -- subjektives Empfinden hervorbringen? Oder allgemeiner gesagt: Wie kann etwas Physisches etwas Nichtphysisches, subjektive Zustände erzeugen? Ob es der Zahnschmerz ist, die Freude beim Anblick der eigenen Kinder oder der Geschmack eines edlen Weins, sie alle haben denselben Ursprung in der Aktivität von Nervengewebe, im Bewusstsein. Christof Koch forscht seit Jahren über das Thema Bewusstsein. In einer Art Bestandsaufnahme zeigt er den derzeitigen Stand der Forschung auf, an dem auch maßgeblich Wissenschaftler wie Francis Crick, Ned Block, David Chalmers, Stanislas Dehaene, Giulio Tononi und Wolf Singer mitgewirkt haben. Ihm erscheint nicht als Widerspruch, mit naturwissenschaftlichen, empirischen Methoden erklären zu wollen, wie Gefühle entstehen. Wir sind uns der meisten Dinge, die in unserem Kopf vorgehen, nicht bewusst. Koch postuliert, dass Zombies ohne Bewusstsein in weiten Teilen unser Leben steuern, auch wenn wir der festen Überzeugung sind, darüber selbst zu bestimmen. Seiner Meinung nach wird es gelingen, empfindungsfähige Maschinen zu bauen - er liefert eine erste Vorlage hierfür im Buch. Er reflektiert so diverse Aspekte wie die Unterscheidung zwischen Aufmerksamkeit und Bewusstsein, das Unbewusste, die Physik und Biologie des freien Willen, Hunde, den Ring der Nibelungen, den Glauben an einen persönlichen Gott und Traurigkeit. Kochs Buch ist mehr als ein wissenschaftlicher Überblick - es ist zudem Bekenntnis, Autobiographie und futuristische Spekulation.

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Abstract

Roboter werden immer schlauer, schon bald werden sie das menschliche Gehirn überflügeln. Da hilft nur eins, sagt der Hirnforscher Christof Koch vom Allen-Institut für Neurowissenschaft: Wir müssen unser Gehirn aufrüsten.

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Abstract

What links conscious experience of pain, joy, color, and smell to bioelectrical activity in the brain? How can anything physical give rise to nonphysical, subjective, conscious states? Christof Koch has devoted much of his career to bridging the seemingly unbridgeable gap between the physics of the brain and phenomenal experience. This engaging book?part scientific overview, part memoir, part futurist speculation?describes Koch's search for an empirical explanation for consciousness. Koch recounts not only the birth of the modern science of consciousness but also the subterranean motivation for his quest?his instinctual (if "romantic") belief that life is meaningful. Koch describes his own groundbreaking work with Francis Crick in the 1990s and 2000s and the gradual emergence of consciousness (once considered a "fringy" subject) as a legitimate topic for scientific investigation. Present at this paradigm shift were Koch and a handful of colleagues, including Ned Block, David Chalmers, Stanislas Dehaene, Giulio Tononi, Wolf Singer, and others. Aiding and abetting it were new techniques to listen in on the activity of individual nerve cells, clinical studies, and brain-imaging technologies that allowed safe and noninvasive study of the human brain in action. Koch gives us stories from the front lines of modern research into the neurobiology of consciousness as well as his own reflections on a variety of topics, including the distinction between attention and awareness, the unconscious, how neurons respond to Homer Simpson, the physics and biology of free will, dogs, Der Ring des Nibelungen, sentient machines, the loss of his belief in a personal God, and sadness. All of them are signposts in the pursuit of his life's work?to uncover the roots of consciousness

Content

In which I introduce the ancient mind-body problem, explain why I am on a quest to use reason and empirical inquiry to solve it, acquaint you with Francis Crick, explain how he relates to this quest, make a confession, and end on a sad note -- In which I write about the wellsprings of my inner conflict between religion and reason, why I grew up wanting to be a scientist, why I wear a lapel pin of Professor Calculus, and how I acquired a second mentor late in life -- In which I explain why consciousness challenges the scientific view of the world, how consciousness can be investigated empirically with both feet firmly planted on the ground, why animals share consciousness with humans, and why self-consciousness is not as important as many people think it is -- In which you hear tales of scientist-magicians that make you look but not see, how they track the footprints of consciousness by peering into your skull, why you don't see with your eyes, and why attention and consciousness are not the same -- In which you learn from neurologists and neurosurgeons that some neurons care a great deal about celebrities, that cutting the cerebral cortex in two does not reduce consciousness by half, that color is leached from the world by the loss of a small cortical region, and that the destruction of a sugar cube-sized chunk of brain stem or thalamic tissue leaves you undead -- In which I defend two propositions that my younger self found nonsense--you are unaware of most of the things that go on in your head, and zombie agents control much of your life, even though you confidently believe that you are in charge -- In which I throw caution to the wind, bring up free will, Der ring des Nibelungen, and what physics says about determinism, explain the impoverished ability of your mind to choose, show that your will lags behind your brain's decision, and that freedom is just another word for feeling -- In which I argue that consciousness is a fundamental property of complex things, rhapsodize about integrated information theory, how it explains many puzzling facts about consciousness and provides a blueprint for building sentient machines -- In which I outline an electromagnetic gadget to measure consciousness, describe efforts to harness the power of genetic engineering to track consciousness in mice, and find myself building cortical observatories -- In which I muse about final matters considered off-limits to polite scientific discourse: to wit, the relationship between science and religion, the existence of God, whether this God can intervene in the universe, the death of my mentor, and my recent tribulations.